Stephen J Kolb Selected Research

Valproic Acid (Depakote)

6/2015	Spinal Muscular Atrophy Biomarker Measurements from Blood Samples in a Clinical Trial of Valproic Acid in Ambulatory Adults.
2/2014	SMA valiant trial: a prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy.

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Stephen J Kolb Research Topics

Disease

23	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2022 - 07/2005
3	Motor Neuron Disease (Primary Lateral Sclerosis) 01/2021 - 08/2012
3	Disease Progression 01/2021 - 12/2017
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2021 - 01/2014
2	Spinal Diseases (Disease, Spinal) 02/2006 - 07/2005
2	Muscular Atrophy (Muscle Atrophy) 02/2006 - 07/2005
1	Nervous System Diseases (Neurological Disorders) 01/2022
1	Fatigue 01/2021
1	Nausea 01/2021
1	Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy) 01/2021
1	Rare Diseases (Rare Disease) 12/2017
1	Premature Obstetric Labor (Premature Labor) 11/2017
1	Hearing Loss (Hearing Impairment) 01/2017
1	Muscular Diseases (Myopathy) 01/2017
1	Distal Myopathies (Distal Muscular Dystrophy) 01/2017
1	Hoarseness 01/2017
1	Cardiomyopathies (Cardiomyopathy) 01/2017
1	X-Linked Bulbo-Spinal Atrophy 07/2015
1	Muscle Weakness 03/2015
1	Peripheral Nerve Injuries 08/2012
1	Frontotemporal Lobar Degeneration (Degeneration, Frontotemporal Lobar) 05/2007
1	Frontotemporal Dementia (Semantic Dementia) 05/2007
1	Stroke (Strokes) 01/2003

Drug/Important Bio-Agent (IBA)

12	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2014
10	Proteins (Proteins, Gene)FDA Link 01/2021 - 07/2005
4	nusinersenIBA 01/2022 - 01/2021
3	Small Nuclear Ribonucleoproteins (snRNP)IBA 06/2012 - 07/2005
2	Biological ProductsIBA 01/2021 - 03/2016
2	Valproic Acid (Depakote)FDA LinkGeneric 06/2015 - 02/2014
1	Inosine FDA Link 01/2021
1	Ketoglutaric Acids (Ketoglutaric Acid)IBA 01/2021
1	NAD (NADH)IBA 01/2021
1	reldesemtivIBA 01/2021
1	neurofilament protein LIBA 01/2021
1	ZolgensmaIBA 01/2019
1	RibonucleoproteinsIBA 01/2018
1	Pharmaceutical PreparationsIBA 12/2017
1	Myosin Heavy Chains (Myosin Heavy Chain)IBA 01/2017
1	Antisense OligonucleotidesIBA 03/2016
1	salicylhydroxamic acid (SHAM)IBA 03/2016
1	Hexosaminidase A (Hex A)IBA 07/2015
1	Complement System Proteins (Complement)IBA 07/2015
1	Heavy MetalsIBA 07/2015
1	Monoclonal AntibodiesIBA 01/2014
1	Crystallins (Crystallin)IBA 08/2012
1	Small Heat-Shock ProteinsIBA 08/2012
1	SMN Complex ProteinsIBA 08/2007
1	Heterogeneous-Nuclear Ribonucleoproteins (Informatin)IBA 05/2007
1	Heterogeneous Nuclear Ribonucleoprotein A1IBA 05/2007

Therapy/Procedure

9	Therapeutics 01/2021 - 01/2014
1	Cesarean Section (Caesarean Section) 11/2017
1	Subacute Care 01/2003